BT-114143
BT-114143 is a plasminogen activation inhibitor, with an IC50 of 8.42 μM. BT-114143 can be used in the research of hemorrhagic diseases caused by hyperfibrinolysis, such as traumatic bleeding, severe menstrual bleeding, postpartum hemorrhage, and complications of hemophilia[1].
Product Specifications
CAS Number
[2796343-04-7]
UNSPSC
12352005
Target
PAI-1
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Cardiovascular Disease
Smiles
O=P(O)(C1=CC=C(CNCC2)C2=N1)O
Molecular Formula
C8H11N2O3P
Molecular Weight
214.16
References & Citations
[1]Ji S, et al. Discovery of BT-114143, a Novel and Potent Phosphoric Acid-Containing Small-Molecule Plasminogen Activation Inhibitor for Hyperfibrinolysis. J Med Chem. 2025 Mar 27;68 (6) :6084-6099.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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