Antitumor agent-199

Antitumor agent-199 (Compound 4b) is an antitumor agent. Antitumor agent-199 exhibits significant antiproliferative activity against multiple tumor cell lines. Antitumor agent-199 can induce autophagy in cancer cells via the ATG5/ATG7 pathway and can be used in the study of cancer[1].

Product Specifications

CAS Number

[3063469-69-9]

UNSPSC

12352005

Target

Atg7; Autophagy

Related Pathways

Autophagy

Field of Research

Cancer

Smiles

COC1=CC(NC2=CC=NC3=CC(OCCCCCOC4=CC=C5C(NC6=CC=CC(OC)=C6)=CC=NC5=C4)=CC=C23)=CC=C1

Molecular Formula

C37H36N4O4

Molecular Weight

600.71

References & Citations

[1]Liang Y, et al. Synthesis and in vitro and in vivo evaluation of novel bivalent quinolines as antitumor agents via targeting autophagy in cervical cancer. Eur J Med Chem. 2025 Apr 15;288:117421.