SPB07935
SPB07935 inhibits the plasmepsin II in Plasmodium falciparum and can be used as an antimalarial agent. SPB07935 regulates the life cycle of P. falciparum, inhibits the growth of Plasmodium strains FcB1 and 3D7 with IC50 of 8 μM and 4.7 μM[1].
Product Specifications
CAS Number
[634190-75-3]
UNSPSC
12352005
Target
Parasite
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=[N+]([O-])C1=CN=C(S1)SC2=NN=C(C3=CC=CO3)N2C(C=C4)=CC=C4OCC5=CC=CC=C5
Molecular Formula
C22H15N5O4S2
Molecular Weight
477.52
References & Citations
[1]Valiente PA, et al., Discovery of a Noncompetitive Open-Flap Selective Inhibitor of Plasmepsin II with Antiplasmodial Activity. J Chem Inf Model. 2025 Feb 24;65 (4) :2038-2051.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
![Rabbit Monoclonal Azurocidin/CAP37/HBP Antibody (421) [Janelia Fluor 646]](https://cdn.genprice.uk/genprice/uk/genprice4.webp)
NBP2-89594JF646 0.1 mL
Rabbit Monoclonal Azurocidin/CAP37/HBP Antibody (421) [Janelia Fluor 646]
Ask
View Details 
035446-ML550 100 µL
FAM38B, NT (PIEZO2, C18orf30, C18orf58, FAM38B, Piezo-type mechanosensitive ion channel component 2, Protein FAM38B) (MaxLight 550) discontinued discontinued
Ask
View Details ![CD45 / LCA Mouse Monoclonal Antibody [Clone ID: K252-1E4]](https://cdn.genprice.uk/genprice/uk/genprice2.webp)
