SMU-1k

SMU-1k is a highly effective and broad-spectrum antiviral agent. SMU-1k inhibits ZIKV and DENV-2 with EC50s of 7.08 and 3.96 μM, respectively. SMU-1k significantly inhibits NS5 protein expression and restores the level of STAT2[1].

Product Specifications

UNSPSC

12352211

Target

Dengue Virus

Related Pathways

Anti-infection

Applications

COVID-19-anti-virus

Field of Research

Infection

Smiles

O=S(C1=CC=C(NC([C@H]2C(C)(C)[C@H]2/C=C(Cl)/C(F)(F)F)=O)C=C1)(C3=CC=C(NC([C@H]4C(C)(C)[C@H]4/C=C(Cl)/C(F)(F)F)=O)C=C3)=O

Molecular Formula

C30H28Cl2F6N2O4S

Molecular Weight

697.52

References & Citations

[1]Lin R, et al. Design, synthesis and biological evaluation of dapsone derivatives with broad-spectrum antiviral activity. Eur J Med Chem. 2025 May 8;293:117717.