MS7131
MS7131 is a USP1-recruiting DUBTACs. MS7131 effectively reduces histone H3 lysine 27 trimethylation and significantly suppresses the proliferation and clonogenicity of cancer cells[1].
Product Specifications
UNSPSC
12352211
Target
Deubiquitinase
Related Pathways
Cell Cycle/DNA Damage
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
CCOC(CCNC1=NC(C2=NC=CC(CCCN(C(CCOCCOCCNC(CCC3=CC=CC=C3C4=NC=C(C(NCC5=CC=CN=C5)=N4)C)=O)=O)C)=C2)=NC(N6CCC7=CC=CC=C7CC6)=C1)=O
Molecular Formula
C55H67N11O6
Molecular Weight
978.19
References & Citations
[1]Chao Qian, et al. Harnessing the Deubiquitinase USP1 for Targeted Protein Stabilization. J Am Chem Soc. 2025 Apr 30;147 (17) :14564-14573.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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