(±) 5 (6) -EET Ethanolamide

(±) 5 (6) -EET Ethanolamide is a metabolite of Anandamide (HY-10863) generated via oxidation by cytochrome P450 enzymes. (±) 5 (6) -EET Ethanolamide is also a selective cannabinoid receptor 2 (CB2) agonist. (±) 5 (6) -EET Ethanolamide has Ki values of 11.4 μM and 8.9 nM for human CB1 and CB2, respectively . (±) 5 (6) -EET Ethanolamide can be used in research on immunomodulation and neuroinflammation[1].

Product Specifications

UNSPSC

12352211

Target

Cannabinoid Receptor; Cytochrome P450

Related Pathways

GPCR/G Protein; Metabolic Enzyme/Protease; Neuronal Signaling

Field of Research

Inflammation/Immunology; Neurological Disease

Smiles

CCCCC/C=C\C/C=C\C/C=C\C[C@H]1O[C@H]1CCCC(NCCO)=O

Molecular Formula

C22H37NO3

Molecular Weight

363.53

References & Citations

[1]Snider NT, et al. A cytochrome P450-derived epoxygenated metabolite of anandamide is a potent cannabinoid receptor 2-selective agonist. Mol Pharmacol. 2009 Apr;75 (4) :965-72.