BQ0413

BQ0413 exhibits good affinity to PSMA with a KD of 89 pM. BQ0413 exhibits good uptake and internalization property with an internalization rate of 44% in PC3-pip cell. BQ0413 can be used as tumor imaging agent when labeled with 99mTc[1].

Product Specifications

CAS Number

[3055338-52-5]

UNSPSC

12352005

Target

PSMA

Related Pathways

Immunology/Inflammation

Field of Research

Cancer

Smiles

OC([C@H](CCC(O)=O)NC(N[C@@H](CCCCNC([C@H](CC1=CC(C=CC=C2)=C2C=C1)NC([C@H](CC3=CC=C(O)C=C3)NC(CCCCCCCNC([C@H](CCCCNC(CNC(C(NC(C(NC(C(CCC(O)=O)NC(CS)=O)=O)CCC(O)=O)=O)CCC(O)=O)=O)=O)NC(C)=O)=O)=O)=O)=O)C(O)=O)=O)=O

Molecular Formula

C69H96N12O24S

Molecular Weight

1509.63

References & Citations

[1]Bezverkhniaia E, et al., Influence of Molecular Design on the Tumor Targeting and Biodistribution of PSMA-Binding Tracers Labeled with Technetium-99m. Int J Mol Sci. 2024 Mar 23;25 (7) :3615.