2N12B
2N12B is a bioreducible ionizable lipid containing disulfide bonds. 2N12B can be used to prepare lipid nanoparticles (LNPs) for the delivery of mRNA in vitro and in vivo. Lipid nanoparticles containing 2N12B can deliver siRNA to inhibit retinal neovascularization[1].
Product Specifications
CAS Number
[3067164-96-6]
UNSPSC
12352211
Target
Liposome
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Metabolic Disease
Smiles
O=C(CCN(CCN(CCC(OCCSSCCCCCCCC)=O)C)CCC(OCCSSCCCCCCCC)=O)OCCSSCCCCCCCC
Molecular Formula
C42H82N2O6S6
Molecular Weight
903.50
References & Citations
[1]Cao X, et al. A potent bioreducible ionizable lipid nanoparticle enables siRNA delivery for retinal neovascularization inhibition. Eur J Pharm Biopharm. 2024 Jun;199:114296.
Shipping Conditions
Room temperature
Scientific Category
Oligonucleotides
Clinical Information
No Development Reported
Curated Selection
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