ACHM-025
ACHM-025 is a prodrug, which is selectively activated by AKR1C3 to a nitrogen mustard DNA alkylating agent. ACHM-025 can be used for the research of cancer, such as leukemia[1].
Product Specifications
CAS Number
[2377718-85-7]
UNSPSC
12352005
Target
Others
Related Pathways
Others
Field of Research
Cancer
Purity
98.06
Smiles
O=S(C1=CC([N+]([O-])=O)=CC=C1N(CCOS(=O)(C)=O)CCOS(=O)(C)=O)(N2CCN(CC2)C)=O
Molecular Formula
C17H28N4O10S3
Molecular Weight
544.62
References & Citations
[1]Toscan CE, et al. The third generation AKR1C3-activated prodrug, ACHM-025, eradicates disease in preclinical models of aggressive T-cell acute lymphoblastic leukemia. Blood Cancer J. 2024 Nov 6;14 (1) :192.
Shipping Conditions
Room Temperature
Storage Conditions
4°C (Powder, protect from light, stored under nitrogen)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
C2414-93-PE 100 µL
CD62E (LECAM, E-Selectin, Endothelial Leukocyte Adhesion Molecule) (PE) discontinued
Ask
View Details 
C2099-74E-FITC 100 µL
G-Protein Coupled Receptor 2 (G-Protein Coupled Receptor 2 (C-C chemokine receptor type 10, CC-CKR-10, C-C CKR-10, CCR-10, GPR2) (FITC) discontinued
Ask
View Details