Thalidomide-4-piperidineacetaldehyde

Thalidomide-4-piperidineacetaldehyde is an E3 ligase ligand and linker conjugate and can be used to synthesize PROTAC H122 (HY-172113) [1].

Product Specifications

CAS Number

[2222115-36-6]

UNSPSC

12352005

Target

E3 Ligase Ligand-Linker Conjugates

Related Pathways

PROTAC

Field of Research

Others

Smiles

O=C(CC1)NC(C1N(C2=O)C(C(C2=C3)=CC=C3N(CC4)CCC4CC=O)=O)=O

Molecular Formula

C20H21N3O5

Molecular Weight

383.40

References & Citations

[1]Lu Y, et al. Selective Degradation of TEADs by a PROTAC Molecule Exhibited Robust Anticancer Efficacy In Vitro and In Vivo. J Med Chem. 2025 Jan 13.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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