NLRP3-IN-68

NLRP3-IN-68 (Compound 2d) is a 1,3,4-oxadiazole derivative. NLRP3-IN-68 has strong anti-inflammatory and antioxidant activities, which can inhibit inflammatory cytokines secretion, iNOS expression and NLRP3 inflammasome activation. NLRP3-IN-68 can be used in the research of anti-inflammatory drugs[1].

Product Specifications

UNSPSC

12352005

Target

NO Synthase; NOD-like Receptor (NLR)

Related Pathways

Immunology/Inflammation

Field of Research

Inflammation/Immunology

Smiles

FC1=CC=C(C=C1)CCC2=NN=C(O2)/C=C/C3=CC(O)=C(C=C3)O

Molecular Formula

C18H15FN2O3

Molecular Weight

326.32

References & Citations

[1]Sun J, et al. Synthesis of bioisosteres of caffeic acid phenethyl ester: 1,3,4-oxadiazole derivatives containing a catechol fragment with anti-inflammatory activities in vitro and in vivo. Bioorg Chem. 2025 Jan 3;155:108123.