NLRP3-IN-68
NLRP3-IN-68 (Compound 2d) is a 1,3,4-oxadiazole derivative. NLRP3-IN-68 has strong anti-inflammatory and antioxidant activities, which can inhibit inflammatory cytokines secretion, iNOS expression and NLRP3 inflammasome activation. NLRP3-IN-68 can be used in the research of anti-inflammatory drugs[1].
Product Specifications
UNSPSC
12352005
Target
NO Synthase; NOD-like Receptor (NLR)
Related Pathways
Immunology/Inflammation
Field of Research
Inflammation/Immunology
Smiles
FC1=CC=C(C=C1)CCC2=NN=C(O2)/C=C/C3=CC(O)=C(C=C3)O
Molecular Formula
C18H15FN2O3
Molecular Weight
326.32
References & Citations
[1]Sun J, et al. Synthesis of bioisosteres of caffeic acid phenethyl ester: 1,3,4-oxadiazole derivatives containing a catechol fragment with anti-inflammatory activities in vitro and in vivo. Bioorg Chem. 2025 Jan 3;155:108123.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
INOS; NLRP3
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