Lipid I97

Lipid I97 is an ionizable lipid derived from vitamin B5 (pKa = 6.23) . Lipid I97 can be used to generate lipid nanoparticles (LNPs) for mRNA delivery in vivo. Lipid I97 can be studied in research for enhancing mRNA transfection efficiency and long-term stability as well as formulation of mRNA vaccines[1].

Product Specifications

CAS Number

[3046404-81-0]

UNSPSC

12352211

Target

Liposome

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer; Inflammation/Immunology

Smiles

CCCCCCCCC(CCCCCC)COC(CCCC(OCC(C)(C)[C@H](C(NCCC(OCCN(C)C)=O)=O)OC(CCCC(OCC(CCCCCC)CCCCCCCC)=O)=O)=O)=O

Molecular Formula

C55H102N2O11

Molecular Weight

967.41

References & Citations

[1]Yoo S, et al., Novel Less Toxic, Lymphoid Tissue-Targeted Lipid Nanoparticles Containing a Vitamin B5-Derived Ionizable Lipid for mRNA Vaccine Delivery. Adv Healthc Mater. 2025 Mar;14 (7) :e2403366.