AR ligand 42
AR ligand 42 is a androgen receptor ligand. AR ligand 42 can be used to synthesize androgen receptor PROTAC degrader ITRI-90 (HY-171808) [1].
Product Specifications
CAS Number
[1240300-27-9]
UNSPSC
12352005
Target
Androgen Receptor; Ligands for Target Protein for PROTAC
Related Pathways
PROTAC; Vitamin D Related/Nuclear Receptor
Field of Research
Endocrinology
Smiles
FC(F)(C1=NN=C2N1N=C(CC2)N3CCC(CC3)C4=CC=C(C=C4)O)F
Molecular Formula
C17H18F3N5O
Molecular Weight
365.35
References & Citations
[1]Hung CL, et al. Targeting androgen receptor and the variants by an orally bioavailable Proteolysis Targeting Chimeras compound in castration resistant prostate cancer. EBioMedicine. 2023 Apr;90:104500.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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