FL-166
FL-166 is a SARS coronavirus main protease (Mpro) inhibitor (Ki: 40 nM) . FL-166 exerts its inhibitory effect by targeting a cluster of serine residues near the active site of the protease. FL-166 can be used in the study of SARS-CoV[1].
Product Specifications
CAS Number
[693235-40-4]
UNSPSC
12352005
Target
SARS-CoV; Virus Protease
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C(C1=CC(B(O)O)=CC([N+]([O-])=O)=C1)NC2=CC=C(NC(C3=CC(B(O)O)=CC([N+]([O-])=O)=C3)=O)C=C2
Molecular Formula
C20H16B2N4O10
Molecular Weight
493.98
References & Citations
[1]Yang H, et al. Drug design targeting the main protease, the Achilles' heel of coronaviruses. Curr Pharm Des. 2006;12 (35) :4573-90.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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