CC-1069
CC-1069, a structural analog of thalidomide (HY-14658), is a TNF-α inhibitor that inhibits endothelial. CC-1069 can be used to study angiogenesis-dependent tumors such as gliomas[1].
Product Specifications
CAS Number
[167887-03-8]
UNSPSC
12352005
Target
TNF Receptor
Related Pathways
Apoptosis
Field of Research
Cancer
Smiles
O=C(CC(N1C(C2=C(C1=O)C=CC=C2)=O)C3=CC=C(C(OC)=C3)OC)N
Molecular Formula
C19H18N2O5
Molecular Weight
354.36
References & Citations
[1]Moreira AL, et al. Thalidomide and a thalidomide analogue inhibit endothelial cell proliferation in vitro. J Neurooncol. 1999 Jun;43 (2) :109-14.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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