TRC4186
TRC4186 is a potent advanced glycation end-product (AGE) inhibitor. TRC4186 demonstrates AGE-breaking activities in vitro and improvement in the endothelial and myocardial function in animal models of diabetes mellitus. TRC4186 can be used for complications associated with diabetes research[1].
Product Specifications
CAS Number
[357625-50-4]
UNSPSC
12352005
Target
Others
Related Pathways
Others
Field of Research
Metabolic Disease
Smiles
O=C(C1=CC=C[N+](CC(C2=CC=CS2)=O)=C1)NNS(=O)(C)=O.[Cl-]
Molecular Formula
C13H14ClN3O4S2
Molecular Weight
375.85
References & Citations
[1]Chandra KP, et al. Phase I clinical studies of the advanced glycation end-product (AGE) -breaker TRC4186: safety, tolerability and pharmacokinetics in healthy subjects. Clin Drug Investig. 2009;29 (9) :559-75.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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