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YNT-3708

YNT-3708 is an orexin receptor (OXR) agonist, with EC50 values of 14.6 nM and 277 nm for OX1R and OX2R, respectively[1].

Product Specifications

CAS Number

[2923137-99-7]

UNSPSC

12352005

Target

Orexin Receptor (OX Receptor)

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Smiles

O=C(N(C)C1CCCC2=C1C=C(NS(=O)(C3=CC(/C=C/C(NC4=CC=NC=C4)=O)=CC=C3OC)=O)C=C2)CC5=CC=CC(OC)=C5

Molecular Formula

C35H36N4O6S

Molecular Weight

640.75

References & Citations

[1]Keita Iio, et al. Design and Synthesis of Orexin 1 Receptor-Selective Agonists. J Med Chem. 2023 Apr 27;66 (8) :5453-5464.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

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