ZM522
ZM522 is a CD73 inhibitor with an IC50 value of 0.56 μM. ZM522 effectively increases the levels of interferon-γ (INF-γ) and enhances immune activity by regulating the activation status of T cells. ZM522 holds promise for research in the fields of immunology and cancer therapy[1].
Product Specifications
CAS Number
[1454575-38-2]
UNSPSC
12352211
Target
CD73
Related Pathways
Immunology/Inflammation
Field of Research
Cancer; Inflammation/Immunology
Smiles
O=C([C@]1(CC[C@H]2C(C)=C)[C@@]2([H])[C@@]3([H])CC[C@]4([H])[C@@]5(C)CC[C@H](OC(C6=CC=C(F)C=C6)=O)C(C)(C)[C@]5([H])CC[C@@]4(C)[C@]3(C)CC1)O
Molecular Formula
C37H51FO4
Molecular Weight
578.80
References & Citations
[1]Zhang Y, et al. Application of a fluorine strategy in the lead optimization of betulinic acid to the discovery of potent CD73 inhibitors. Steroids. 2022 Dec;188:109112.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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