HPH-15
HPH-15 is an anti-migration compound that inhibits cell migration by binding to hnRNP U or suppressing TGF-β signaling. In addition, HPH-15 can also inhibit epithelial-mesenchymal transition (EMT) . HPH-15 holds promise for research in the fields of anti-tumor metastasis and anti-fibrosis[1].
Product Specifications
CAS Number
[1009838-93-0]
UNSPSC
12352005
Hazard Statement
H302, H315, H319, H335
Target
DNA/RNA Synthesis; TGF-β Receptor
Related Pathways
Cell Cycle/DNA Damage; TGF-beta/Smad
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Purity
99
Smiles
S=C(C1=CC=CC(C(NCCSC(C)(C)C)=S)=N1)NCCSC(C)(C)C
Molecular Formula
C19H31N3S4
Molecular Weight
429.73
Precautions
H302, H315, H319, H335
References & Citations
[1]Toma T, et al. An anti-cell migration compound that binds to hnRNP U and suppresses nuclear deformation. Bioorg Chem. 2025 Mar;156:108215.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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