Antidiabetic agent 7

Antidiabetic agent 7 (Compound 5m) is hyperglycemic inhibitor. Antidiabetic agent 7 exhibits promising potency to stimulate GLUT4 translocation in skeletal muscle cells via activating AMPK-dependent pathway. Antidiabetic agent 7 reduces blood glucose levels. Antidiabetic agent 7 shows favorable pharmacokinetic properties. Antidiabetic agent 7 is potential to be used for anti-hyperglycemic research[1].

Product Specifications

UNSPSC

12352005

Target

AMPK; GLUT

Related Pathways

Epigenetics; Membrane Transporter/Ion Channel; PI3K/Akt/mTOR

Field of Research

Metabolic Disease

Smiles

O=C(C1=C(C)NC(NC1C2=CC=C(Cl)C=C2Cl)=O)NC3=CC=C(C(N4C)=NC5=C(C=CC=C5)C4=O)C=C3

Molecular Formula

C27H21Cl2N5O3

Molecular Weight

534.39

References & Citations

[1]Jaiswal AK, et al. Design, synthesis, and biological evaluation of quinazolinone-dihydropyrimidinone as a potential anti-diabetic agent via GLUT4 translocation stimulation. Eur J Med Chem. 2025 Feb 6;288:117366.