CDK2-IN-40
CDK2-IN-40 is a CDK2 (Cyclin dependent kinase 2) inhibitor, extracted from patent WO 2024/254245 A1 (Example 1) . CDK2-IN-40 inhibits CDK2/Cyclin E1 with an IC50 of ≤ 10 nM[1].
Product Specifications
CAS Number
[3065079-44-6]
UNSPSC
12352005
Target
CDK
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Purity
99.80
Solubility
DMSO : 125 mg/mL (ultrasonic)
Smiles
CC(C)OC1=C(N=CN2C1=NC(NC3CCOCC3)=N2)C4=CNN=C4
Molecular Formula
C16H21N7O2
Molecular Weight
343.38
References & Citations
[1]HUMMEL Joshua, et al. BICYCLIC AMINES AS CDK2 INHIBITORS. WO 2024/254245 A1. World Intellectual Property Organization. 12.12.2024
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
CDK2
Available Sizes
Curated Selection
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