IRX5010

IRX5010 (IRX4647F), an analogue of IRX4647, is a highly selective RARγ nuclear receptor agonist. IRX5010 demonstrates inhibition of in vivo growth of EMT-6 triple negative breast cancer[1].

Product Specifications

CAS Number

[856683-59-5]

Product Name Alternative

IRX4647F

UNSPSC

12352005

Target

RAR/RXR

Related Pathways

Metabolic Enzyme/Protease; Vitamin D Related/Nuclear Receptor

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

CC1(C)C2=C(C=CC(C(/C=C/C3=CC=C(C(O)=O)C=C3F)=N/O)=C2)C(C)(C)CC1

Molecular Formula

C24H26FNO3

Molecular Weight

395.47

References & Citations

[1]Sanders M E, et al. IRX5010 (IRX4647F), a Highly Selective RARγ Nuclear Receptor Agonist Compound Inhibits In Vivo Growth of Murine EMT-6 Triple Negative Breast Cancer and Human JIMT-1 Her2+ Breast Cancer By Induction of Tumor-Infiltrating Effector Memory T-cells[J].