PTPN22-IN-2
PTPN22-IN-2 (Compound 8b-19) is a PTPN22 inhibitor with an IC50 of 250 nM. PTPN22-IN-2 can be used for research in the field of immunomodulation[1].
Product Specifications
UNSPSC
12352005
Target
Phosphatase
Related Pathways
Metabolic Enzyme/Protease
Field of Research
Inflammation/Immunology
Smiles
OC1=C(C(O)=O)C=C(C(/C=C/C2=CC=CC(Cl)=C2)=C(C3=CC=C(OCC(NC4CC4)=O)C=C3)O5)C5=C1
Molecular Formula
C28H22ClNO6
Molecular Weight
503.93
References & Citations
[1]Jassim BA, et al. Structure-activity relationship studies and design of a PTPN22 inhibitor with enhanced isozyme selectivity and cellular efficacy. Eur J Med Chem. 2025 Feb 5;283:117129.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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