GHP-88309
GHP-88309 is a broad-spectrum, orally active antiviral agent targeting paramyxoviruses, that targets the viral polymerase, interupts the viral RNA synthesis, and inhibits respiratory syncytial virus (RSV), measles virus (MeV), and canine distemper virus (CDV) with EC50 of 0.06-1.2 μM. GHP-88309 exhibits anti-infectious efficacy in mouse models[1].
Product Specifications
CAS Number
[1269267-87-9]
UNSPSC
12352005
Target
DNA/RNA Synthesis; RSV
Related Pathways
Anti-infection; Cell Cycle/DNA Damage
Field of Research
Infection
Smiles
O=C(C1=C(C=CC=C1C2=CC=CC3=C2C=CN=C3)F)N
Molecular Formula
C16H11FN2O
Molecular Weight
266.27
References & Citations
[1]Cox RM, et al., Orally efficacious broad-spectrum allosteric inhibitor of paramyxovirus polymerase. Nat Microbiol. 2020 Oct;5 (10) :1232-1246.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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