AR ligand-33
AR ligand-33 is the ligand for androgen receptor, that can be used for synthesis of PROTAC AR Degrader-8 (HY-170329) as the target protein ligand[1].
Product Specifications
UNSPSC
12352005
Target
Androgen Receptor; Ligands for Target Protein for PROTAC
Related Pathways
PROTAC; Vitamin D Related/Nuclear Receptor
Field of Research
Cancer
Smiles
OC1=CC=C(C(C)(C2=CC=C(OCC3=NC(N4CCOCC4)=CC=C3)C=C2)C)C=C1
Molecular Formula
C25H28N2O3
Molecular Weight
404.50
References & Citations
[1]Ha S, et al., Discovery of a highly potent, N-terminal domain-targeting degrader of AR-FL/AR-V7 for the treatment of prostate cancer. Eur J Med Chem. 2025 Jan 15;282:117079.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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