AS2690168 (hydrochloride)
AS2690168 hydrochloride is an orally active RANKL signal transduction inhibitor which suppresses RANKL-induced osteoclastogenesis of RAW264 cells. AS2690168 can be utilized in research related to pathological osteolysis[1].
Product Specifications
CAS Number
[1393899-47-2]
UNSPSC
12352005
Target
RANKL/RANK
Related Pathways
NF-κB
Field of Research
Others
Smiles
FC1=CC(F)=C(CNC2=NC(C3=CC=CC=N3)=NC=C2OC)C(F)=C1.Cl
Molecular Formula
C17H14ClF3N4O
Molecular Weight
382.77
References & Citations
[1]Morikawa N, et al. Pharmacological characterization of AS2690168, a novel small molecule RANKL signal transduction inhibitor. Eur J Pharmacol. 2022 Jun 5;924:174941.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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