5′-Guanidinonaltrindole
5′-Guanidinonaltrindole (GNTI) is a selective kappa opioid receptor antagonist[1].
Product Specifications
CAS Number
[219655-56-8]
Product Name Alternative
GNTI
UNSPSC
12352005
Target
Opioid Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O[C@]12[C@@]34C5=C(C[C@@]2([H])N(CC4)CC6CC6)C=CC(O)=C5O[C@@]3([H])C7=C(C8=CC(NC(N)=N)=CC=C8N7)C1
Molecular Formula
C27H29N5O3
Molecular Weight
471.55
References & Citations
[1]Munro TA, et al. Long-acting κ opioid antagonists nor-BNI, GNTI and JDTic: pharmacokinetics in mice and lipophilicity. BMC Pharmacol. 2012 May 29;12:5.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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