2002-G12
2002-G12 (compound 5a) is an Aβ42 inhibitor that can reduce Aβ42 toxicity by 76%. 2002-G12 can be used in Alzheimer's research[1].
Product Specifications
CAS Number
[313666-93-2]
UNSPSC
12352005
Target
Amyloid-β
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Smiles
NC1=CC=C2N=C(C3=C(C4=NC5=C(N4)C=C(N)C=C5)C=CC=C3)NC2=C1
Molecular Formula
C20H16N6
Molecular Weight
340.38
References & Citations
[1]Chen J, et al. Small molecule microarrays enable the discovery of compounds that bind the Alzheimer's Aβ peptide and reduce its cytotoxicity. J Am Chem Soc. 2010 Dec 1;132 (47) :17015-22.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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