TrkA-IN-7
TrkA-IN-7 (Compound 4) is an inhibitor of Tropomyosin Receptor Kinase A (TrkA) with a Kd value of 40 μM[1].
Product Specifications
CAS Number
[296888-45-4]
UNSPSC
12352005
Target
Trk Receptor
Related Pathways
Neuronal Signaling; Protein Tyrosine Kinase/RTK
Field of Research
Cancer
Smiles
OC1=C(C=C(C)C=C1)C2=NNC(C3=C(C=CC=C3)[N+]([O-])=O)=C2
Molecular Formula
C16H13N3O3
Molecular Weight
295.29
References & Citations
[1]Park H, et al. Identification of novel inhibitors of tropomyosin-related kinase A through the structure-based virtual screening with homology-modeled protein structure[J]. Journal of chemical information and modeling, 2011, 51 (11) : 2986-2993.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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