DfrA1-IN-1
DfrA1-IN-1 (Compound DC6) is an orally active DfrA1 inhibitor with strong binding ability to DfrA1. DfrA1-IN-1 can be used in research related to trimethoprim-resistant bacterial infections[1].
Product Specifications
CAS Number
[2488069-21-0]
UNSPSC
12352005
Target
Bacterial
Related Pathways
Anti-infection
Field of Research
Infection
Smiles
O=C(NCC1=NC2=CC=CC=C2N1C)CCC[C@@H]3[C@@]4([H])CCCN([C@@]54[H])CCC[C@@]5([H])CN3C(C6=CC=CN=C6)=O
Molecular Formula
C30H38N6O2
Molecular Weight
514.66
References & Citations
[1]Hasnat S, et al. High throughput screening identifies potential inhibitors targeting trimethoprim resistant DfrA1 protein in Klebsiella pneumoniae and Escherichia coli. Sci Rep. 2025 Feb 28;15 (1) :7141.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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