BRCA2-IN-2

BRCA2-IN-2 (Compound 3i) has a strong binding affinity to the BRCA2 protein. BRCA2-IN-2 can inhibit the proliferation of breast cancer cells and scavenge DPPH free radicals. BRCA2-IN-2 has anti-tumor and antioxidant activities[1].

Product Specifications

UNSPSC

12352211

Target

Reactive Oxygen Species (ROS)

Related Pathways

Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology

Smiles

NS(=O)(C1=CC=C(C=C1)/N=N/C2=CC=C(C(/C=N/C3=NC=CC=C3)=C2)O)=O

Molecular Formula

C18H15N5O3S

Molecular Weight

381.41

References & Citations

[1]Rezaeianzadeh O, et al. Synthesis and application of diazenyl sulfonamide-based schiff bases as potential BRCA2 active inhibitors against MCF-7 breast cancer cell line. Sci Rep. 2025 Feb 24;15 (1) :6661.