BAY-277
BAY-277, a chemical probe, is a METAP2 degrader, with IC50 values of 5.8 nM and 5.9 nM for hMETAP2 and mMETAP2, respectively[1].
Product Specifications
UNSPSC
12352211
Target
MetAP
Related Pathways
Metabolic Enzyme/Protease
Applications
Cancer-programmed cell death
Field of Research
Cancer
Smiles
O=C(N1CCC(C2=CC=C3C(CN(C4C(NC(CC4)=O)=O)C3=O)=C2)CC1)CCCCCN(CC5)CCC5C6=CC=C(C=C6)OC7=NN8C(C9=C7CCCC9)=NN=C8
Molecular Formula
C44H52N8O5
Molecular Weight
772.93
References & Citations
[1]Overview for BAY-277 a degrader of METAP2.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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