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Ferroptosis-IN-18

Ferroptosis-IN-18 (51), a promethazine derivative, shows strong anti-ferroptosis and anti-oxidant properties. Ferroptosis-IN-18 (51) can be used in the research for intracerebral hemorrhage (ICH) [1].

Product Specifications

CAS Number

[2247525-20-6]

UNSPSC

12352005

Target

Ferroptosis; Glutathione Peroxidase

Related Pathways

Apoptosis; Metabolic Enzyme/Protease

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

CC(C(C=C1N2)=CC=C1SC3=C2C=CC=C3)C4=CC=C(N5CCN(C)CC5)C=C4

Molecular Formula

C25H27N3S

Molecular Weight

401.57

References & Citations

[1]Bing-Qiao Wang, et al. A novel ferroptosis inhibitor phenothiazine derivative reduces cell death and alleviates neurological impairments after cerebral hemorrhage. Neuropharmacology. 2025 Jun 15:271:110399.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Isoform

GPX4

Curated Selection

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