STAT3-IN-41

STAT3-IN-41 (Compound 16) is a prodrug of compound 1. STAT3-IN-41 slowly releases compound 1 inhibiting STAT3 signaling pathway. STAT3-IN-41 shows antitumor activity against lung cancer, hepatocellular carcinoma and pancreatic cancer[1].

Product Specifications

UNSPSC

12352005

Target

STAT

Related Pathways

JAK/STAT Signaling; Stem Cell/Wnt

Field of Research

Cancer

Smiles

O=C1O[C@@H]2[C@H](O3)[C@@]3(C)CC/C=C(CC(F)(F)F)\CC[C@H]2[C@@H]1CN(C)C.OC(/C=C/C(O)=O)=O

Molecular Formula

C22H30F3NO7

Molecular Weight

477.47

References & Citations

[1]Duan X, et al. Discovery of novel fluorine-containing parthenolide analogues as potential antitumor agents. Eur J Med Chem. 2025 Mar 15;286:117283.