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ZSA-51

ZSA-51 is a potent and orally active STING agonist. ZSA-51 shows anticancer activity. ZSA-51 remodeles immune microenvironment both in tumor and lymph node[1].

Product Specifications

CAS Number

[3084542-49-1]

UNSPSC

12352005

Target

STING

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Purity

97.27

Solubility

DMSO : 6.67 mg/mL (ultrasonic; warming; heat to 60°C)

Smiles

COC(CCN1C(C2=C(C3=CC(OC)=C(C=C3S2)OC)C1=O)=O)=O

Molecular Formula

C16H15NO6S

Molecular Weight

349.36

References & Citations

[1]Zhao HY, et al. An oral tricyclic STING agonist suppresses tumor growth through remodeling of the immune microenvironment. Cell Chem Biol. 2025 Jan 24:S2451-9456 (25) 00004-2.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Curated Selection

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