KT32
KT32 (10c) is a potent dual inhibitor of HDAC and Topo II α. KT32 induces cell death through apoptosis[1].
Product Specifications
CAS Number
[3028278-67-0]
UNSPSC
12352211
Target
Apoptosis; HDAC; Topoisomerase
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Epigenetics
Field of Research
Cancer
Smiles
O=C(NO)CCCCOC(C=C1C(C=CC(C)(C)O1)=C2N(C)C3=C4C=CC=C3)=C2C4=O
Molecular Formula
C24H26N2O5
Molecular Weight
422.47
References & Citations
[1]Kavya et al. Semisynthesis of Glycosmis pentaphylla Alkaloid Derivatives: Pyranoacridone-Hydroxamic Acid Cytotoxic Conjugates with HDAC and Topoisomerase II α Dual Inhibitory Activity. J Nat Prod. 2025 Jan 8.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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