PSP205
PSP205 is a potent anticancer agent. PSP205 shows cytotoxicity. PSP205 induces apoptosis. PSP205 induces ER-stress-mediated autophagy. PSP205 increases the protein expression of LC3BII and increases the CHOP and spliced XBP1 at the mRNA and protein levels[1].
Product Specifications
CAS Number
[837408-39-6]
UNSPSC
12352005
Target
Apoptosis; Autophagy
Related Pathways
Apoptosis; Autophagy
Field of Research
Cancer
Smiles
ClC1=CC=CC(CN2N=NC3=C(O)N=C(C4CCCN(S(=O)(C5=CC=C(S(=O)(N6CCC(C)CC6)=O)C=C5)=O)C4)N=C32)=C1
Molecular Formula
C28H32ClN7O5S2
Molecular Weight
646.18
References & Citations
[1]Soma Samanta, et al. PSP205, a Novel Phenyl Sulfonyl Piperidine, Induces Apoptotic Cell Death in Colon Cancer by Modulating Coat Protein Complex-Mediated Vesicle Trafficking. ACS Pharmacology & Translational Science. 2025, 9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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