PKR-IN-1
PKR-IN-1 (Compound 5s) is a pyruvate kinase (PK) inhibitor that has antifungal activity, with an EC50 of 0.21 μg/mL for R. solani[1].
Product Specifications
CAS Number
[3057531-75-3]
UNSPSC
12352005
Target
Fungal; Pyruvate Kinase
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Applications
COVID-19-immunoregulation
Field of Research
Infection
Smiles
ClC1=NSC(C2=CSC(C3=NN=C(C(Cl)(Cl)Cl)O3)=N2)=C1Cl
Molecular Formula
C9HCl5N4OS2
Molecular Weight
422.53
References & Citations
[1]Gao W, et al. Pyruvate Kinase-Based Novel 2-Thiazol-2-yl-1,3,4-oxadiazoles Discovery as Fungicidal Highly Active Leads. J Agric Food Chem. 2025 Jan 15;73 (2) :1075-1085.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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