5R (6S) -EET
5R (6S) -EET is the metabolite of Arachidonic acid (HY-109590) . 5R (6S) -EET activates the synthesis of endogenous prostaglandin (PGE2), which inhibits the Na+ absorption, increases the intracellular Ca2+, and promotes the depolarization of transmembrane voltage. 5R (6S) -EET exhibits stereoselectivity with less effectness than 5S (6R) -EET (HY-168382A) [1].
Product Specifications
CAS Number
[98103-46-9]
UNSPSC
12352211
Target
Endogenous Metabolite; Prostaglandin Receptor
Related Pathways
GPCR/G Protein; Metabolic Enzyme/Protease
Field of Research
Others
Smiles
OC(CCC[C@@H]1[C@@H](O1)C/C=C\C/C=C\C/C=C\CCCCC)=O
Molecular Formula
C20H32O3
Molecular Weight
320.47
References & Citations
[1]Sakairi Y, et al., 5,6-EET inhibits ion transport in collecting duct by stimulating endogenous prostaglandin synthesis. Am J Physiol. 1995 May;268 (5 Pt 2) :F931-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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