NS 1231
NS 1231 is a neurotrophic-like compound with neuroprotective effect. NS 1231 can rescue nerve growth factor (NGF) -differentiated PC12 cells from death induced by withdrawal of trophic factors. NS 1231 can stimulate NGF-induced neurite outgrowth of undifferentiated PC12 cells. NS 1231 can be used for the research of neurological disease, such as stroke[1].
Product Specifications
CAS Number
[309711-72-6]
UNSPSC
12352005
Target
Others
Related Pathways
Others
Field of Research
Neurological Disease
Smiles
O=C1NC2=C(C=C(C3=CC=C(Cl)C=C3)C4=C2CCCC4)/C1=N/O
Molecular Formula
C18H15ClN2O2
Molecular Weight
326.78
References & Citations
[1]Dagø L, et al. NS 1231, a novel compound with neurotrophic-like effects in vitro and in vivo. J Neurochem. 2002 Apr;81 (1) :17-24.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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