Arpromidine
Arpromidine (BU-E-50) is the agonist for histamine H2 receptor and the antagonist for histamine H1 receptor. Arpromidine exhibits positive inotropic effect with less risks in causing arrhythmias. Arpromidine can be used in research of congestive heart failure[1].
Product Specifications
CAS Number
[106669-71-0]
Product Name Alternative
BU-E-50
UNSPSC
12352005
Target
Histamine Receptor
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Neuronal Signaling
Field of Research
Cardiovascular Disease
Smiles
FC1=CC=C(C(CCNC(NCCCC2=CN=CN2)=N)C3=NC=CC=C3)C=C1
Molecular Formula
C21H25FN6
Molecular Weight
380.46
References & Citations
[1]Buschauer A. Synthesis and in vitro pharmacology of arpromidine and related phenyl (pyridylalkyl) guanidines, a potential new class of positive inotropic drugs. J Med Chem. 1989 Aug;32 (8) :1963-70.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Isoform
H1 Receptor; H2 Receptor
Curated Selection
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