Penicinoline
Penicinoline (Marinamide) (Compound 1), a pyrrolyl 4-quinolinone alkaloid, is a microbial secondary metabolite. Penicinoline can be isolated from endophytic fungus Penicillium sp. Penicinoline has antimalarial activity against Chloroquine (HY-17589A) sensitive strain (pf3d7) and against Chloroquine resistant strain (pfDd2) of plasmodium falciparum. Penicinoline also has strong insecticidal activity against Aphis gossypii and selective anticancer effect with significant cytotoxicity for 95-D and HepG2 cells[1][2].
Product Specifications
CAS Number
[1214268-60-6]
Product Name Alternative
Marinamide
UNSPSC
12352005
Target
Endogenous Metabolite; Parasite
Related Pathways
Anti-infection; Metabolic Enzyme/Protease
Field of Research
Cancer; Infection
Smiles
O=C(C1=C(C2=CC=CN2)NC3=C(C=CC=C3)C1=O)O
Molecular Formula
C14H10N2O3
Molecular Weight
254.24
References & Citations
Shipping Conditions
Room temperature
Scientific Category
Natural Products
Clinical Information
No Development Reported
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