LOC1886
LOC1886 is a covalent inhibitor of GPX4 with slightly lower potency than RSL3 and ML162[1].
Product Specifications
CAS Number
[951948-38-2]
UNSPSC
12352005
Target
Glutathione Peroxidase
Related Pathways
Apoptosis; Metabolic Enzyme/Protease
Field of Research
Cancer
Smiles
O=C(N1C=NC=C1)C2=CC3=C(N2)C=CC=C3OC
Molecular Formula
C13H11N3O2
Molecular Weight
241.25
References & Citations
[1]Liu H, et al. Small-molecule allosteric inhibitors of GPX4. Cell Chem Biol. 2022 Dec 15;29 (12) :1680-1693.e9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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