K-832
K-832 is an orally active IL-1β secretion inhibitor. K-832 can be used in the research of rheumatoid arthritis[1][2].
Product Specifications
CAS Number
[225666-85-3]
UNSPSC
12352005
Target
Interleukin Related
Related Pathways
Immunology/Inflammation
Field of Research
Inflammation/Immunology
Smiles
O=C1C=C(C2=CC=C(Cl)C=C2)C(C3=CC=C(SC)C=C3)=NN1CC4=CC=CC=C4
Molecular Formula
C24H19ClN2OS
Molecular Weight
418.94
References & Citations
[1]Dumont F J. The interleukin-1 families of cytokines and receptors: therapeutic potential for immunomodulation and the treatment of inflammatory disorders. Expert Opinion on Therapeutic Patents, 2006, 16 (7) : 879-912.|[2]Halim S A, et al. Attempt to explore the binding mechanism of IL-1β inhibitors via molecular docking studies. Med. Chem, 2015, 5 (10) : 452-457.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
Phase 2
Isoform
IL-1
Curated Selection
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