Polθ-IN-7
Polθ-IN-7 (example 12) is a DNA polymerase theta (Polθ) inhibitor with a Ki of 1.27 nM[1].
Product Specifications
CAS Number
[2923356-52-7]
UNSPSC
12352005
Target
DNA/RNA Synthesis
Related Pathways
Cell Cycle/DNA Damage
Field of Research
Cancer
Smiles
O=C1[C@@]2([H])N(C3=CC(C(F)(F)F)=CC(C)=N3)C(C[C@]2([H])CN(C4=C(C)C=CC=C4N1C)CCN5CCN(CC5)C)=O
Molecular Formula
C28H35F3N6O2
Molecular Weight
544.61
References & Citations
[1]Owen Davis, et al. Heterocyclic compounds for use in the treatment of cancer. WO2023067355A1.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Curated Selection
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