R419

R419 is a Complex I inhibitor. R419 has anti-cancer activity against liver cancer[1].

Product Specifications

CAS Number

[1356629-00-9]

UNSPSC

12352005

Target

Oxidative Phosphorylation

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Smiles

N#CC1=CC=C(CN2CCC(CC2)NC(C3=CN=C(C(N4CCC(CC4)C(C5=CC=C(C=C5)OC)=O)=O)C=C3)=O)C=C1

Molecular Formula

C33H35N5O4

Molecular Weight

565.66

References & Citations

[1]Huang Y, et al. Synthesis and biological evaluation of Complex I inhibitor R419 and its derivatives as anticancer agents in HepG2 cells. Bioorg Med Chem Lett. 2018 Sep 15;28 (17) :2957-2960.

Shipping Conditions

Room temperature

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Curated Selection

Explore Other Products

Discover premium biology products from our extensive collection of 20M+ items

MBS9931646 Inquire

Cavy Alpha/Beta Hydrolase Domain-Containing Protein 1 (ABHD1) ELISA Kit

Ask

View Details

NBP2-70948B 0.1 mL

Mouse Monoclonal HSF2 Antibody (OTI3E1) [Biotin]

Ask

View Details

A1125-25A-PE 200 µL

AKT2, phosphorylated (Ser474) (RAC-beta Serine/Threonine-protein Kinase, RAC-PK-beta, Protein Kinase Akt-2, Protein Kinase B, beta, PKB beta) (PE)

Ask

View Details