Vistusertib (Standard)

Vistusertib (Standard) is the analytical standard of Vistusertib. This product is intended for research and analytical applications. Vistusertib (AZD2014) is an ATP competitive mTOR inhibitor with an IC50 of 2.81 nM. AZD2014 inhibits both mTORC1 and mTORC2 complexes.

Product Specifications

CAS Number

[1009298-59-2]

UNSPSC

12352100

Target

Apoptosis; Autophagy; mTOR; Reference Standards

Related Pathways

Apoptosis; Autophagy; Others; PI3K/Akt/mTOR

Field of Research

Cancer

Smiles

O=C(NC)C1=CC=CC(C2=CC=C3C(N=C(N4[C@@H](C)COCC4)N=C3N5[C@@H](C)COCC5)=N2)=C1

Molecular Formula

C25H30N6O3

Molecular Weight

462.54

References & Citations

[1]Guichard SM, et al. AZD2014, an inhibitor of mTORC1 and mTORC2, is highly effective in ER+ breast cancer when administered using intermittent or continuous schedules. Mol Cancer Ther. 2015 Nov;14 (11) :2508-18.