Talsupram

Talsupram is a selective noradrenaline inhibitor that has a high affinity for the noradrenaline transporter. Talsupram exhibits anti-hyperalgesic effects. Talsupram can decrease ethanol intake to the levels prior to REM-induced deprivation in rat model[1][2].

Product Specifications

CAS Number

[21489-20-3]

UNSPSC

12352005

Target

Adrenergic Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Endocrinology; Neurological Disease

Smiles

CC1(C)C2=C(C=CC=C2)C(C3=CC=CC=C3)(CCCNC)S1

Molecular Formula

C20H25NS

Molecular Weight

311.48

References & Citations

[1]Hacısüleyman, L., et al., (2022) . Analgesic Effects of Vilazodone, Indatraline, and Talsupram in a Rat Model of Neuropathic Pain. Turkish journal of pharmaceutical sciences, 19 (3), 336–342.|[2]Aalto, J., & Kiianmaa, K. (1986) . REM-sleep deprivation-induced increase in ethanol intake: role of brain monoaminergic neurons. Alcohol (Fayetteville, N.Y.), 3 (6), 377–381.