SQ109 (Standard)

SQ109 (Standard) is the analytical standard of SQ109. This product is intended for research and analytical applications. SQ109 is a potent inhibitor of the trypomastigote form of the parasite, with IC50 for cell killing of 50±8 nM. SQ109, targets MmpL3, is an antitubercular agent.

Product Specifications

CAS Number

[502487-67-4]

Product Name Alternative

NSC 722041 (Standard)

UNSPSC

12352211

Target

Antibiotic; Bacterial; Parasite; Reference Standards

Related Pathways

Anti-infection; Others

Field of Research

Infection

Smiles

C/C(C)=C/CC/C(C)=C/CNCCNC1[C@H]2C[C@H]3C[C@@H]1C[C@H](C3)C2

Molecular Formula

C22H38N2

Molecular Weight

330.55

References & Citations

[1]Veiga-Santos P, et al. SQ109, a new drug lead for Chagas disease. Antimicrob Agents Chemother. 2015 Apr;59 (4) :1950-61.|[2]Jia L, et al. Pharmacodynamics and pharmacokinetics of SQ109, a new diamine-based antitubercular drug. Br J Pharmacol. 2005 Jan;144 (1) :80-7|[3]Jia L, et al. Interspecies pharmacokinetics and in vitro metabolism of SQ109. Br J Pharmacol. 2006 Mar;147 (5) :476-85.